TargetDisk Product Line

Our TargetDisk product line provides molecular insights that pave the way for a comprehensive understanding of the human skin. It provides access to biomarker-based molecular patterns, enabling a deeper exploration of difficult cases of (inflammatory) skin diseases.

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TargetDisk Product Line: Expanding Molecular Profiling in Skin Research

Explore biomarkers and molecular pathways of the skin

At Dermagnostix, we believe that true innovation in dermatology begins at the molecular level.

With the TargetDisk product line, we are opening a new chapter in molecular skin research, providing dermatologists and dermatopathological laboratories with powerful tools to uncover the biological mechanisms behind skin health and disease. TargetDisks are specifically designed to measure selected target and reference genes, providing the data needed to calculate a score that enables comparison of gene signatures across different skin samples.

TargetDisk expands the possibilities of molecular profiling by combining cutting-edge gene expression analysis with the proven reliability of the Dermagnostix Analyzer. This seamless integration allows performance of automated, high-throughput assays with precision, reproducibility, and efficiency.

Your Benefits at a Glance

  • Seamless integration with the Dermagnostix Analyzer: Achieve effortless workflow automation with full compatibility of the TargetDisk product line with the Dermagnostix Analyzer, enabling smooth system integration, higher efficiency, and consistent lab performance.
  • Accelerate innovation in dermatological research: Expand your molecular profiling capabilities and unlock new insights in skin biology. Gain insights, and accelerate discoveries in dermatology.
  • Compare different skin samples to identify similarities and differences based on the calculated score and the expression of specific target and reference genes. Determine how the measured target genes contribute to or influence key biological roles across the various skin samples.
  • Lead the future of skin science: Position your institution at the forefront of dermatological innovation. Strengthen your reputation in fundamental molecular skin analysis and stay ahead in the global scientific landscape.
TargetDisk

Erysk-TargetDisk

Now available
Tissue type: FFPE skin samples

Measurement of biomarkers LCK and HOMER1 in FFPE-samples

Erysk-TargetDisk is a molecular assay for the analysis of the biomarkers LCK and HOMER1, which have been studied for their role in distinguishing early stage mycosis fungoides (MF) from benign inflammatory dermatoses such as eczema and psoriasis.¹ Erysk-TargetDisk provides access to biomarker-based molecular patterns that enable deeper exploration of difficult cases, especially when clinical and histological findings are inconclusive. This allows for a deeper insight into the biological processes of the skin and provides additional context that can help advance clinical methodology development.

The TargetDisk product line is for Research Use Only (RUO). Not for use in diagnostic procedures.

¹Meinel, M., et al.: LCK and HOMER1 gene expression-based classifier distinguishes early mycosis fungoides from eczema and psoriasis. medRxiv (2025): 2025-10.

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PE-TargetDisk

Coming Soon
Tissue type: fresh skin samples

Measurement of the biomarkers NOS2 and CCL27 in fresh skin samples

The PE-TargetDisk assay enables analysis of NOS2 and CCL27 gene expression from fresh human skin samples using the Dermagnostix system. These genes have been widely studied in the context of the inflammatory skin conditions psoriasis and eczema.¹

The TargetDisk product line is for Research Use Only (RUO). Not for use in diagnostic procedures.

¹Quaranta, M., et al. (2014): Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema. Science translational medicine 6.244

Pattern-TargetDisk

Coming Soon
Tissue type: FFPE skin samples

Characterization of Molecular Patterns in Inflammatory Skin Research

The molecular pattern approach in dermatology involves clustering inflammatory skin profiles according to gene expression data from skin samples to uncover the mechanisms underlying skin conditions.¹ Pattern-TargetDisk enables the analysis of molecular markers and the identification of inflammation-related skin profiles for research purposes. It facilitates exploratory studies, supporting biomarker discovery, molecular stratification, and the grouping of study participants.

The TargetDisk product line is for Research Use Only (RUO). Not for use in diagnostic procedures.

¹Eyerich, K., & Eyerich, S. (2018). Immune response patterns in non‐communicable inflammatory skin diseases. Journal of the European Academy of Dermatology and Venereology, 32(5), 692-703., Seiringer, P., Garzorz-Stark, N., & Eyerich, K. (2022). T-Cell‒Mediated autoimmunity: Mechanisms and future directions. Journal of Investigative Dermatology, 142(3), 804-810.

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