At Dermagnostix, we develop molecular diagnostic tests to support dermatologists and dermatopathologists in achieving precise and objective diagnoses. We create cutting-edge easy to-use molecular diagnostics for dermatology to advance clinical practice and improve therapeutic outcome.
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Transforming Dermatological Diagnostics for a Healthier Future
Skin diseases are common and affect millions of people worldwide. Conditions such as psoriasis and atopic dermatitis (eczema) have increased significantly, while new therapies have greatly improved treatment options. However, diagnosis in dermatology still relies largely on visual assessment and histology, which can be challenging as many inflammatory skin diseases appear very similar. This often leads to uncertainty and delays in treatment decisions.
Molecular diagnostics offers a more precise approach by analyzing gene expression and biomarkers directly in the skin. It provides additional insights beyond what is visible and helps to differentiate diseases such as psoriasis and eczema better.
Dermagnostix bridges this gap with molecular diagnostic solutions that integrate easily into clinical workflows. By delivering fast, objective, and biology-based insights, we support healthcare professionals in making more confident decisions and improving patient care.
Flohr C, Hay R (2021): Putting the burden of skin diseases on the global map. Br J Dermatol 184(2): 189-190.
Andersen LK, Davis MD (2013): The epidemiology of skin and skin-related diseases: a review of population-based studies performed by using the Rochester Epidemiology Project. Mayo Clinic proceedings 88:1462-7.
Nutten S (2015): Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab 66 Suppl 1:8-16.
The top 20 drugs by worldwide sales in 2023. (2024, May 28). Fierce Pharma. Accessed February 21, 2025, von
PsorX-LabDisk
The First Molecular Test for the Differential Diagnosis of Psoriasis and Eczema
Psoriasis or Eczema? Psoriasiform eczema versus eczematized psoriasis? The difference truely matters with specific treatment options now available for both diseases.
PsorX-LabDisk (CE-IVD) is a groundbreaking molecular diagnostic tool that quantitatively differentiates between psoriasis and eczema by analyzing the expression of two marker genes, NOS2 and CCL27, in the skin. Designed to enhance diagnostic precision, it empowers pathologists and dermatopathologists with accurate, patient-specific molecular insights. By bridging the gap between histological and molecular data, PsorX-LabDisk supports confident clinical decision-making and supports personalized care in dermatology.
Your molecular support for inflammatory dermatoses.
The PE TargetDisk (RUO) enables the measurement of the biomarkers NOS2 and CCL27 from fresh human skin samples. By measuring these molecular markers, the disk supports a deeper understanding of the biological patterns of the inflammatory dermatoses psoriasis and eczema. With molecular profiling, PE-TargetDisk delivers objective, biologically grounded information quickly and simply.Â
Measurement of biomarkers LCK and HOMER1 in FFPE-samples
Erysk-TargetDisk is a molecular assay for the analysis of selected biomarker genes, including LCK and HOMER1, which have been studied in the scientific literature for their role in T-cell-mediated pathways. Through our TargetDisk product line, we empower scientists to understand the molecular mechanisms underlying skin function by equipping them with state-of-the-art molecular tools to explore skin biology.
The LabDisk-Analyzer is a state-of-the-art diagnostic medical device designed for advanced molecular workflows in pathology and beyond!
This fully automated system streamlines and accelerates molecular workflows – from sample preparation to signal detection – minimizing manual steps and user errors. Its compact, intuitive design supports laboratories in delivering precise results efficiently while complying with IVDR standards, setting a new benchmark for modern molecular diagnostics.
“Pathology is changing – by using modern methods such as molecular diagnostics in combination with a trained view through the microscope, we achieve greater precision and objectivity and set new quality standards. The innovative Dermagnostix products are therefore a perfect addition to our service portfolio. The excellent customer service should also be highlighted: if you have any questions or challenges, they will always find a quick solution. As a pioneers in pathological molecular diagnostics, we greatly appreciate the cooperation with Dermagnostix.”
Prof. Dr. Dr. Jörg Kriegsmann
University Hospital Augsburg - Dermatohistopathology Laboratory
“We are extremely satisfied with the customer service. Every time we had a question or faced a challenge, support was available by phone or email. The friendly and efficient communication with the Team and the quick problem-solving really stood out to us. We had no concerns about using molecular diagnostics in dermatopathology, as we are an innovative and forward-thinking lab.”
Franziska Augustiner
Specialist in dermatology and venereology and professor for translational research of inflammatory skin diseases
“The molecular diagnostic possibilities Dermagnostix offers will be the future in pattern diagnostics of dermatological diseases and ultimately treatment selection. Great to see how the platform automizes complex procedures in a closed and fast system.“
Prof. Kristian Reich, M.D., Ph.D
Dermatologisches Zentrum Zürich
“PsorX can also be valuable in cases of initial discrepancy – a staged histology revealed a match between the histological image and the gene expression signature of the markers NOS2 and CCL27 in stage 12.”
“Most of my routine cases are inflammatory diseases, especially eczema and psoriasis. Most of them are straightforward in diagnoses. However, some cause diagnostic dilemmas. In these cases, the PsorX-LabDisk is extremely useful in supporting my histological diagnosis quickly and easily. Furthermore, its user-friendly handling saves me time compared to other molecular biological tests.”
Prof. Denisa Kacerovská, M.D., PhD
Chief Physician at the Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at the University of Osnabrück and BG Klinikum Hamburg
„Molecular diagnostics will fundamentally change our diagnostic world. It enables significantly more precise diagnoses and thus provides the basis for targeted, individually tailored therapies. This allows us to better understand disease patterns today and make more informed therapeutic decisions than ever before.“
Prof. Dr. Christoph Skudlik
University Hospital Münster, former president of the International Society of Dermatopathology
„New innovations are often either overly praised or prematurely criticized, but the truth usually lies somewhere in between. Molecular diagnostics is not a substitute, but a valuable additional component in diagnosis. It broadens our perspective and enables us to move beyond black-and-white thinking to arrive at more informed diagnoses.“
Prof. Dr. Dieter Metze
University Hospital Augsburg - Dermatohistopathology Laboratory
“Using the Dermagnostix system, including the LabDisk-Analyzer and PsorX-LabDisk, has significantly improved our ability to differentiate between psoriasis and eczema diagnoses with more precision. It serves as an excellent diagnostic support tool alongside histology. Implementing the system into our daily lab routine was smooth, and all our staff found it easy to understand.”
Franziska Augustiner
Find Dermagnostix partner laboratories near you!
Looking for dermatopathology laboratory using molecular diagnostics? Explore our international network of Dermagnostix partner laboratories.
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