Early-stage Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), often mimics eczema and psoriasis, clinically and histologically. Clinical presentation and histopathology often overlap with benign inflammatory dermatoses, making a clear distinction difficult, even for experienced specialists.
In routine practice, the diagnostic pathway typically begins with clinical suspicion, followed by skin biopsy and histopathological assessment. In many cases, however, the uncertainty persists until the disease has progressed to the point where it can no longer be treated as effectively as it could have been in the early stages. This is where molecular information can add value.
The Erysk-TargetDisk (RUO) enables the measurement of MF-associated gene expression biomarkers LCK and HOMER1 from standard FFPE skin samples. This provides an additional layer of biological insight to support the characterization of challenging cases.